遗传性牙齿萌出障碍的诊断和治疗

doi:10.13591/j.cnki.kqyx.2026.01.005

Abstract

Abstract:

Tooth eruption disorders represent common developmental anomalies in dentistry, among which hereditary types pose significant challenges in diagnosis and treatment due to their complex molecular mechanisms and diverse clinical manifestations. This review systematically summarizes the etiology, clinical features, and management strategies of five major hereditary tooth eruption disorders, including primary failure of eruption(PFE), cleidocranial dysplasia(CCD), osteopetrosis(OP), pyknodysostosis, and GAPO syndrome. For diagnosis, we emphasize an integrated approach combining characteristic clinical presentations, imaging evaluations, and genetic testing to achieve precise classification. Regarding treatment, we propose multidisciplinary collaboration as the foundation for developing personalized sequential treatment plans, while highlighting the importance of genetic counseling and long-term management. This review aims to provide both theoretical foundations and practical guidance for the systematic understanding and precise management of these disorders.

Key words: hereditary tooth eruption disorders, pathogenic genes, multidisciplinary collaboration, personalized treatment

CLC Number:

R781.2

LIU Yang, SUN Xinyi, DU Jinying, SONG Rui, YANG Yi, ZHENG Shuguo. Diagnosis and treatment of hereditary tooth eruption disorders[J]. Stomatology, 2026, 46(1): 27-34.

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Diagnosis and treatment of hereditary tooth eruption disorders

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