关键词: 非综合征唇腭裂, 锥形束CT, 上气道

Abstract:

Objective To conduct a three-dimensional comparative study on upper airway symmetry between patients with non-syndromic cleft lip and palate and populations with skeletal Class Ⅲ. Methods Fifty-one cases of non-syndromic cleft lip and palate patientsand 50 cases of skeletal Class Ⅲ populationswere included. Cone-beam CT was taken, and Dolphin 3D 11.9 software was used for three-dimensional measurement and analysis. SPSS 25.0 software package was used for independent sample test to compare the volume, height and minimum area of the upper airway. Results The minimum cross-sectional area of the upper airway nasopharyngeal segment of patients with non-syndromic cleft lip and palate was larger than that of skeletal Class Ⅲ population(P<0.01). The upper airway pharyngeal segment height of patients with non-syndromic cleft lip and palate was smaller than that of skeletal Class Ⅲ population(P<0.01). There was no significant difference in the other segments of the upper airway(P>0.05). Conclusion There are differences in the three-dimensional structure of the upper airway between NSCLP patients and skeletal Ⅲ population, except for the similarity in the glossopharyngeal segment, indicating that the cause of cleft lip and palate is not only abnormal anatomical structure, but also affected by other functional factors. Therefore, respiratory problems need multi-disciplinary diagnosis and treatment.

Key words: non-syndromic cleft lip, cone-beam CT, upper airway