仿生湿黏附水凝胶在口腔敷料中的应用研究进展

doi:10.13591/j.cnki.kqyx.2025.09.011

摘要/Abstract

摘要：

仿生湿黏附材料通过模拟生物体的黏附特性,实现在湿润或水下环境中的强力粘接。相比于传统医用胶黏剂,这类材料通常具有生物相容性好、黏附性强和可调控的物理化学性质。尽管仿生湿粘接材料在口腔黏膜给药、口腔内伤口处理和种植手术等领域有广泛应用,但目前尚缺乏系统性综述。该文总结了仿生湿黏附材料的湿黏附机制以及在不同场景下的应用,旨在为新的口腔内敷料设计提供思路和方法。

关键词: 仿生材料, 湿粘接剂, 贻贝, 章鱼吸盘, 藤壶胶

Abstract:

Biomimetic wet-adhesive hydrogels mimic the adhesive properties of biological organisms to achieve strong bonding in moist environments. Compared to conventional medical adhesives, these materials are characterized by enhanced biocompatibility, robust adhesion, and adjustable physicochemical properties. Although biomimetic wet-adhesive hydrogels have been applied in oral mucosal drug delivery, intraoral wound management, and implant surgery, a systematic review is currently lacking. This article aims to summarize the wet-adhesion mechanisms of bio-inspired materials and their applications in various scenarios and to provide insights and methodologies for the design of novel intraoral dressings.

Key words: biomimetic material, wet-adhesives, mussel, octopus sucker, barnacle cement

中图分类号:

R78.1

丁淑雯, 朱佳玉, 赵洁晨, 吴小华, 吴珺华. 仿生湿黏附水凝胶在口腔敷料中的应用研究进展[J]. 口腔医学, 2025, 45(9): 701-706.

DING Shuwen, ZHU Jiayu, ZHAO Jiechen, WU Xiaohua, WU Junhua. Research progress of biomimetic wet-adhesive hydrogel in oral dressings[J]. Stomatology, 2025, 45(9): 701-706.

图/表 1

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