骨免疫微环境在种植体骨结合中的作用

doi:10.13591/j.cnki.kqyx.2022.12.011

Abstract

Abstract: Osseointegration of implants is a dynamic process involving multi-cell and multi-factor. Traditional research has been focusing on bone formation and absorption in osseointegration. With the development of osteoimmunology, studies find that the immune microenvironment of bone plays an important role in the establishment and long-term maintenance of osseointegration. Immune cells regulate bone repair around implants by chemokines and cytokines. Ideal immune microenvironment could promote tissue healing and regeneration to achieve better bone-implant contact. More attention has been given to the regulation of osseointegration and treatment of peri-implantitis via bone immunomodulation. In this article, the immune response process around dental implants was summarized by reviewing relevant literature. At present, there are more studies on macrophages, but few on other immune response cells. There are still many questions about the mechanism of immune response between immune cells and implants remaining to be explained.

Key words: osteoimmunology, osseointegration, implant, macrophage, immunomodulation

CLC Number:

R783.4

YUAN Ying, HUANG Tianyu, WANG Haochen, GONG Ping, XIANG Lin. The role of bone immune microenvironment in implant osseointegration[J]. Stomatology, 2022, 42(12): 1109-1112.

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The role of bone immune microenvironment in implant osseointegration

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