冷冻疗法在口腔黏膜病治疗中的应用

doi:10.13591/j.cnki.kqyx.2023.09.013

Abstract

Abstract:

Cryotherapy is a surgical technique that employs freezing to destroy undesirable tissue. Major advantages of oral cryotherapy include safety, convenience and less side effects. It has been widely used in the treatment of many cutaneous diseases. Because oral mucosa is similar to skin, many diseases occurring in oral mucosa, such as vascular anomalies, mucosal pigmentation, oral ulcer, sialocele, oral lichen planus, oral leukoplakia, are appropriate for this technology. This article mainly discusses the principle, method and application of cryotherapy in the treatment of oral mucosal diseases. Due to its numerousadvantages, including small damage to surrounding tissues, no bleeding, no scar, light pain after treatment, low incidence of secondary infection and simple operation, cryotherapy has the potential to be the first choice or alternative in the treatment of many oral mucosal diseases.

Key words: cryotherapy, tissue freezing, oral mucosal disease

CLC Number:

R781.5

LI Zhenglei, YAN Yujie, TIAN Xin, ZENG Xin, WANG Jiongke, CHEN Qianming. Application of cryotherapy in the treatment of oral mucosal disease[J]. Stomatology, 2023, 43(9): 837-843.

Figures/Tables 2

References 61

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冷冻疗法皮肤病适应证		有效率	复发率
皮肤良性病变	樱桃状血管瘤^[20?-22]	68%~100%	0%
	寻常疣^[23]	45.61%	-
	肥厚性瘢痕和瘢痕疙瘩^[24]	68%~81%	2%
	皮肤纤维瘤^[25]	91.4%	-
	化脓性肉芽肿^[26-27]	90%~100%	2%~9%
	皮脂腺增生^[28]	96.7%	0%
	皮赘^[29]	64.3%	-
	日光性黑子^[30]	100%	0%
	脂溢性角化病^[31]	68%	-
皮肤癌前病变	光化性角化病^[32-33]	57%~97%	2.1%~15.6%
皮肤恶性肿瘤	表浅型基底细胞癌^[34]	99%	1.2%
	鳞状细胞癌^[35]	97%	0.4%~0.8%
	恶性黑素瘤^[36]	-	10%
	卡波西肉瘤^[37]	63%	0%
	Bowen病^[38]	91.7%	14.2%

冷冻疗法口腔黏膜病适应证		有效率	复发率
发生于口腔黏膜的良性病变	牙龈色素沉着^[39]	100%	0%
	发生于口腔黏膜的脉管性疾病^[40]	100%	5%
	唾液腺囊肿^[41]	95.5%	0%
	复发性阿弗他溃疡^[42]	84.7%	-
口腔潜在恶性疾患	口腔扁平苔藓^[43]	76.7%	-
	口腔白斑病^[44]	77.78%	22.22%

Application of cryotherapy in the treatment of oral mucosal disease

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