一氧化氮在牙周炎进展中的作用机制与应用

doi:10.13591/j.cnki.kqyx.2023.10.014

Abstract

Abstract:

Nitric oxide is a small-molecule free radical with a short half-life, which can penetrate the cell membrane and play the role of intercellular signaling. It has been found that nitric oxide plays a dual role in periodontal tissues. Under physiological conditions, it promotes vasodilation, stimulates cytokine expression, regulate bone homeostasis and platelet aggregation; under pathological conditions, it can cause connective tissue destruction and alveolar bone resorption. This article reviews the mechanism of nitric oxide in periodontitis and related application, hoping to providing reference for the future treatment of periodontal diseases.

Key words: nitric oxide, nitric oxide synthase, periodontal tissue, periodontitis

CLC Number:

R781.4

QUNI Sezhen, ZHOU Yanmin. The mechanism and application of nitric oxide in the progression of periodontitis[J]. Stomatology, 2023, 43(10): 935-938.

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The mechanism and application of nitric oxide in the progression of periodontitis

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