矫治力初期牙髓组织HSP70表达及临床意义

Abstract

Abstract: Objective To detect the expression and distribution of HSP70 in human dental pulp tissues and to analyze the influences of orthodontic forces on dental pulp and to use biomechanic principle correctly .Methods 16 patients were randomly assigned to control group and 1d，3d and 7d groups after orthodontics.The test teeth were extracted at the corresponding time and paraffin was prepared.Immunohistochemical method (SABC method) was utilized to localize and examine the expression of HSP70.Results HSP70 was stained inodontoblast,vascular enelothelial cells and some smooth muscle cells.The expression of HSP70 didn′tincreaseobviously in 1d group (P>0.05); it reached the highest level in 3d group especially in smooth muscle cell of vessel wall(P<0.01) and decreased greatly in 7d group.There was no pulp necrosisin all cases.〖WTHZ〗Conclusions〓〖WTBZ〗The changes of HSP70 in dental pulp during orthodontic tooth movement suggest that nitricoxide may play an important role in pulp selfrepair.HSP70 may provide effective protection to pulp tissue with appropriate force.

Key words: hot shock protein70(HSP70), immunohistochemistry, orthodontics, dental pulp

CLC Number:

R783.5

References

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The expression of HSP70 in dental pulp tissues in early orthodntic force and its clinical significance

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