Stomatology ›› 2022, Vol. 42 ›› Issue (3): 276-279.doi: 10.13591/j.cnki.kqyx.2022.03.017

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Research advances in the relationship between human β defensin-2 and oral lichen planus

HUANG Xinzhao, ZHONG Liangjun   

  1. School of Stomatology, Hangzhou Normal University, Hangzhou 311121, China
  • Revised:2021-06-29 Online:2022-03-28 Published:2022-03-21

Abstract: Oral lichen planus (OLP) is a common chronic immune inflammatory disease that affects oral mucosa. However, the exact etiology of OLP has not yet been elucidated and valid diagnosis and treatment for OLP is inhibited by some factors with OLP itself a risk factor for malignant transformation. Therefore, research on the pathogenesis of OLP and treatment for OLP has been receiving much attention. In recent years, some studies have shown that OLP is closely related to human β defensin-2 (hBD-2). This paper attempts to summarize and analyze recent research progress of OLP and hBD-2.

Key words: human β defensin-2, oral lichen planus, antimicrobial peptide, Candida albicans

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