Stomatology ›› 2023, Vol. 43 ›› Issue (6): 556-560.doi: 10.13591/j.cnki.kqyx.2023.06.014

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Advances in research on chronic non-bacterial osteomyelitis

WANG Hanshao,WANG Fang,WANG Yiwen,CHEN Minjie()   

  1. Department of Oral and Maxillofacial Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology, Shanghai 200011, China
  • Revised:2022-08-06 Online:2023-06-28 Published:2023-07-06

Abstract:

Chronic non-bacterial osteomyelitis is a kind of auto-inflammatory bone disease that occurs in children and adolescents, also known as diffuse sclerosing osteomyelitis or chronic recurrent multifocal osteomyelitis. Clinical symptoms are varied and non-specific, and there aren’t specific indicators in laboratory examination, imaging examination and pathological examination. Prone to misdiagnosis or delayed diagnosis, it is still dominated by diagnosis of exclusion at present. This article reviews the pathogenesis, diagnosis and treatment of chronic non-bacterial osteomyelitis.

Key words: chronic non-bacterial osteomyelitis, auto-inflammatory disease, diffuse sclerosing osteomyelitis, chronic recurrent multifocal osteomyelitis

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