累及口腔的IgG4相关疾病研究进展

doi:10.13591/j.cnki.kqyx.2023.12.010

Abstract

Abstract:

IgG4-related disease (IgG4-RD) is a systemic multi-organ fibroinflammatory disease of unknown etiology. Studies suggest that the proliferation and activation of B cells, T cells and their crosstalk may play important roles in the immune response and fibrosis process of the disease. IgG4-RD can involve multiple organs and systems including the maxillofacial region. Salivary glands are the most frequently involved organs in the oral cavity. In addition, other tissues in the oral cavity can also be affected, and the clinical manifestations are heterogeneous. It is difficult to make accurate clinical diagnosis. To this end, this article searches literature reports of IgG4-RD involving oral tissue in recent years, and reviews the IgG4-RD involving oral cavity from the perspective of epidemiology, pathogenesis, clinical manifestation, diagnosis and treatment, combined with the latest diagnostic criteria.

Key words: IgG4-related disease, oral cavity, pathogenesis, diagnosis, treatment

CLC Number:

R781.9

ZHANG Tianyu,JIANG Lu. Research progress of IgG4-related disease in oral cavity[J]. Stomatology, 2023, 43(12): 1106-1111.

Figures/Tables 2

References 50

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