壳聚糖及其衍生物在牙本质粘接修复中的研究进展

doi:10.13591/j.cnki.kqyx.2023.12.014

Abstract

Abstract:

The stability of the hybrid layer formed by adhesive resin systems and dentin collagen fibrils is critical to the success of dentine restoration. The hydrolysis of dentin collagen fibrils by endogenous dentin proteases is responsible for the failure of dentin bonding. Studies have shown than chitosan and its derivatives, as an innovative biomaterial in dentin bonding, could enhance dentin bond strength and the durability of resin-dentin bond. This article reviewed the properties, mechanism and research progress of chitosan and its derivatives in dentin bonding.

Key words: chitosan, dentin bonding, biomodification

CLC Number:

R783.1

GUAN Lanxi,CAI Chen,HUANG Yuting,LI Yang,JIANG Qianzhou. Progress of research on the application of chitosan and its derivatives in dentin bonding[J]. Stomatology, 2023, 43(12): 1129-1133.

References 48

[1]	刘恩言, 李明云. 茶多酚类化合物在牙本质粘接中应用的研究进展[J]. 国际口腔医学杂志, 2020, 47(6):732-738.
[2]	钱鑫, 张志民. 化学交联剂对树脂牙本质粘接稳定性的影响[J]. 口腔医学研究, 2020, 36(3):203-205. doi: 10.13701/j.cnki.kqyxyj.2020.03.003
[3]	Mai S, Wei CC, Gu LS, et al. Extrafibrillar collagen demineralization-based chelate-and-rinse technique bridges the gap between wet and dry dentin bonding[J]. Acta Biomater, 2017, 57: 435-448. doi: S1742-7061(17)30298-2 pmid: 28499631
[4]	孔维婧, 顾新华, 孙健. 不同种类交联剂对牙本质Ⅰ型胶原生物改性作用的研究进展[J]. 中华口腔医学杂志, 2020, 55(2):135-138.
[5]	Braga RR, Fronza BM. The use of bioactive particles and biomimetic analogues for increasing the longevity of resin-dentin interfaces: A literature review[J]. Dent Mater J, 2020, 39(1):62-68. doi: 10.4012/dmj.2019-293 pmid: 31723068
[6]	古丽莎, 吴倩. 化学交联在牙本质粘接修复中的应用及展望[J]. 中华口腔医学研究杂志(电子版), 2019, 13(3):129-135.
[7]	孙翔, 余凡, 许荣宸, 等. 牙本质生物改性与牙本质粘接耐久性[J]. 实用口腔医学杂志, 2021, 37(4):566-569.
[8]	Curylofo-Zotti FA, Fernandes MP, Martins AA, et al. Caries removal with Er: YAG laser followed by dentin biomodification with carbodiimide and chitosan: Wettability and surface morphology analysis[J]. Microsc Res Tech, 2020, 83(2):133-139. doi: 10.1002/jemt.v83.2
[9]	Almeida Curylofo-Zotti F, Scheffel DLS, Macedo AP, et al. Effect of Er: YAG laser irradiation and chitosan biomodification on the stability of resin/demineralized bovine dentin bond[J]. J Mech Behav Biomed Mater, 2019, 91: 220-228. doi: S1751-6161(18)31142-1 pmid: 30597375
[10]	Kmiec M. Chitosan-properties and applications in dentistry[J]. Adv Tissue Eng Regen Med Open Access, 2017, 2(4):1-7.
[11]	Zhang CX, Hui DD, Du C, et al. Preparation and application of chitosan biomaterials in dentistry[J]. Int J Biol Macromol, 2021, 167: 1198-1210. doi: 10.1016/j.ijbiomac.2020.11.073 pmid: 33202273
[12]	Kou S, Peters LM, Mucalo MR. Chitosan: A review of sources and preparation methods[J]. Int J Biol Macromol, 2021, 169: 85-94. doi: 10.1016/j.ijbiomac.2020.12.005 pmid: 33279563
[13]	Machado AHS, Garcia IM, de Souza da Motta A, et al. Triclosan-loaded chitosan as antibacterial agent for adhesive resin[J]. J Dent, 2019, 83: 33-39. doi: S0300-5712(18)30296-3 pmid: 30794843
[14]	Abd El-Hack ME, El-Saadony MT, Shafi ME, et al. Antimicrobial and antioxidant properties of chitosan and its derivatives and their applications: A review[J]. Int J Biol Macromol, 2020, 164: 2726-2744. doi: 10.1016/j.ijbiomac.2020.08.153 pmid: 32841671
[15]	Wang WQ, Meng QY, Li Q, et al. Chitosan derivatives and their application in biomedicine[J]. Int J Mol Sci, 2020, 21(2):487. doi: 10.3390/ijms21020487
[16]	Shariatinia Z. Carboxymethyl chitosan: Properties and biomedicalapplications[J]. Int J Biol Macromol, 2018, 120: 1406-1419. doi: S0141-8130(18)33775-9 pmid: 30267813
[17]	Li XM, Xing RE, Xu CJ, et al. Immunostimulatory effect of chitosan and quaternary chitosan: A review of potential vaccine adjuvants[J]. Carbohydr Polym, 2021, 264: 118050. doi: 10.1016/j.carbpol.2021.118050
[18]	Kong M, Chen XG, Xing K, et al. Antimicrobial properties of chitosan and mode of action: A state of the art review[J]. Int J Food Microbiol, 2010, 144(1):51-63. doi: 10.1016/j.ijfoodmicro.2010.09.012 pmid: 20951455
[19]	Ardean C, Davidescu CM, Nemeş NS, et al. Factors influencing the antibacterial activity of chitosan and chitosan modified by functionalization[J]. Int J Mol Sci, 2021, 22(14):7449. doi: 10.3390/ijms22147449
[20]	Pestov A, Bratskaya S. Chitosan and its derivatives as highly efficient polymer ligands[J]. Molecules, 2016, 21(3):330. doi: 10.3390/molecules21030330 pmid: 26978343
[21]	Silva PV, Guedes DC, Nakadi FV, et al. Chitosan: A new solution for removal of smear layer after root canal instrumentation[J]. Int Endod J, 2013, 46(4):332-338. doi: 10.1111/j.1365-2591.2012.02119.x pmid: 22970844
[22]	Zhou H, Li Q, Wei L, et al. A comparative scanning electron microscopy evaluation of smear layer removal with chitosan and MTAD[J]. Niger J Clin Pract, 2018, 21(1):76-80. doi: 10.4103/1119-3077.224798 pmid: 29411728
[23]	陈彦伶, 张立, 张凌琳, 等. 壳聚糖及其衍生物在口腔疾病防治中的研究进展[J]. 生物工程学报, 2021, 37(7):2322-2333.
[24]	Rizeq BR, Younes NN, Rasool K, et al. Synthesis, bioapplications, and toxicity evaluation of chitosan-based nanoparticles[J]. Int J Mol Sci, 2019, 20(22):5776. doi: 10.3390/ijms20225776
[25]	Rashki S, Asgarpour K, Tarrahimofrad H, et al. Chitosan-based nanoparticles against bacterial infections[J]. Carbohydr Polym, 2021, 251: 117108. doi: 10.1016/j.carbpol.2020.117108
[26]	齐远征, 焦俊杰, 李永丽, 等. 壳聚糖促进口腔软组织修复的研究进展[J]. 现代口腔医学杂志, 2021, 35(6):420-423,414.
[27]	刘卓冉, 李玉梅, 刘俊彦, 等. 口腔抗菌领域中壳聚糖及其衍生物的作用[J]. 中国组织工程研究, 2023, 27(21):3361-3367.
[28]	Gu LS, Cai X, Guo JM, et al. Chitosan-based extrafibrillar demineralization for dentin bonding[J]. J Dent Res, 2019, 98(2):186-193. doi: 10.1177/0022034518805419 pmid: 30326766
[29]	Stenhagen ISR, Rukke HV, Dragland IS, et al. Effect of methacrylated chitosan incorporated in experimental composite and adhesive on mechanical properties and biofilm formation[J]. Eur J Oral Sci, 2019, 127(1):81-88. doi: 10.1111/eos.12584 pmid: 30412313
[30]	Baena E, Cunha SR, Maravić T, et al. Effect of chitosan as a cross-linker on matrix metalloproteinase activity and bond stability with different adhesive systems[J]. Mar Drugs, 2020, 18(5):263. doi: 10.3390/md18050263
[31]	Paschoini VL, Ziotti IR, Neri CR, et al. Chitosan improves the durability of resin-dentin interface with etch-and-rinse or self-etch adhesive systems[J]. J Appl Oral Sci, 2021, 29: e20210356. doi: 10.1590/1678-7757-2021-0356
[32]	Yu F, Luo ML, Xu RC, et al. A novel dentin bonding scheme based on extrafibrillar demineralization combined with covalent adhesion using a dry-bonding technique[J]. Bioact Mater, 2021, 6(10):3557-3567. doi: 10.1016/j.bioactmat.2021.03.024 pmid: 33842741
[33]	Maravić T, Baena E, Mazzitelli C, et al. Endogenous enzymatic activity in dentin treated with a chitosan primer[J]. Int J Mol Sci, 2021, 22(16):8852. doi: 10.3390/ijms22168852
[34]	Neves JG, Marcato PD, de Paula e Silva FWG, et al. Synthesis and characterization of an experimental primer containing chitosan nanoparticles-Effect on the inactivation of metalloproteinases, antimicrobial activity and adhesive strength[J]. Arch Oral Biol, 2021, 127: 105148. doi: 10.1016/j.archoralbio.2021.105148
[35]	蔡明轩, 毛靖, 汪一帆, 等. 脱矿牙本质基质保护策略及其在牙本质-树脂粘接修复中的研究进展[J]. 中华口腔医学杂志, 2021, 56(11):1144-1149.
[36]	Zhao HX, Liao JW, Wu FP, et al. Mechanical strength improvement of chitosan/hydroxyapatite scaffolds by coating and cross-linking[J]. J Mech Behav Biomed Mater, 2021, 114: 104169. doi: 10.1016/j.jmbbm.2020.104169
[37]	Del Carpio-Perochena A, Bramante CM, Duarte MAH, et al. Chelating and antibacterial properties of chitosan nanoparticles on dentin[J]. Restor Dent Endod, 2015, 40(3):195-201. doi: 10.5395/rde.2015.40.3.195 pmid: 26295022
[38]	Adamiak K, Sionkowska A. Current methods of collagen cross-linking: Review[J]. Int J Biol Macromol, 2020, 161: 550-560. doi: S0141-8130(20)33516-9 pmid: 32534089
[39]	Shrestha A, Friedman S, Kishen A. Photodynamically crosslinked and chitosan-incorporated dentin collagen[J]. J Dent Res, 2011, 90(11):1346-1351. doi: 10.1177/0022034511421928
[40]	Almeida Curylofo-Zotti F, Tedesco AC, Lizarelli GTC, et al. Effect of green tea-loaded chitosan nanoparticles on leathery dentin microhardness[J]. Odontology, 2021, 109(4):860-867. doi: 10.1007/s10266-021-00611-6 pmid: 33963944
[41]	Mohamed AM, Nabih SM, Wakwak MA. Effect of chitosan nanoparticles on microtensile bond strength of resin composite to dentin: An in vitro study[J]. Braz Dent Sci, 2020, 23(2):1-10.
[42]	贾玲玲, 万乾炳. 基质金属蛋白酶抑制剂的研究进展[J]. 华西口腔医学杂志, 2017, 35(2):208-214.
[43]	Mazzoni A, Angeloni V, Comba A, et al. Cross-linking effect on dentin bond strength and MMPs activity[J]. Dent Mater, 2018, 34(2):288-295. doi: S0109-5641(17)30581-X pmid: 29179972
[44]	Guo JM, Makvandi P, Wei CC, et al. Polymer conjugation optimizes EDTA as a calcium-chelating agent that exclusively removes extrafibrillar minerals from mineralized collagen[J]. Acta Biomater, 2019, 90: 424-440. doi: 10.1016/j.actbio.2019.04.011
[45]	Zhang ZY, Zhang YZ, Wu ZF, et al. The effect of prime-and-rinse approach using MDP micellar solutions on extrafibrillar demineralization and dentin bond performance[J]. Dent Mater, 2021, 37(5):e300-e313.
[46]	Li BQ, Zhu XM, Ma L, et al. Selective demineralisation of dentine extrafibrillar minerals—a potential method to eliminate water-wet bonding in the etch-and-rinse technique[J]. J Dent, 2016, 52: 55-62. doi: 10.1016/j.jdent.2016.07.008
[47]	Zhou Y, Zhao YM, Han JM. EDTA-chitosan is a feasible conditioning agent for dentin bonding[J]. Clin Oral Invest, 2022, 26(4):3449-3458. doi: 10.1007/s00784-021-04270-3
[48]	Shan T, Huang L, Tay FR, et al. Retention of intrafibrillar minerals improves resin-dentin bond durability[J]. J Dent Res, 2022, 101(12):1490-1498. doi: 10.1177/00220345221103137

Progress of research on the application of chitosan and its derivatives in dentin bonding

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