Abstract: Objective To explore the association between periodontitis and inflammatory bowel diseases. Methods Chinese and English journal databases such as Medline, Pubmed, EMBASE, CBM, CNKI and VIP were searched electronically and examined by hand. The literatures on the association between periodontitis and inflammatory bowel diseases were collected through systematic literature screening and data extraction. Metaanalysis was performed by Revman 5.3.3. Results Nine English trials met the inclusion criteria, including 35 129 participants, 7 676 of whom with inflammatory bowel diseases. The result of Metaanalysis showed that patients with inflammatory bowel diseases（OR=1.66，Z=13.21，P<0.000 01）, Crohn's disease（OR=1.60，Z=11.92，P<0.000 01）or ulcerative colitis（OR=3.33，Z=7.58，P<0.000 01） were more likely to develop chronic periodontitis. Conclusion There is a significant correlation between periodontitis and inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

Key words: periodontitis, inflammatory bowel disease, evidence- based medicine, Meta-analysis