Stomatology ›› 2024, Vol. 44 ›› Issue (2): 152-155.doi: 10.13591/j.cnki.kqyx.2024.02.014

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The role of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease

DAI Ke,DAI Zhouli,LIU Rongchang,ZHA Guangyu,CAO Mingguo()   

  1. College of Medicine, Lishui University, Lishui 323000, China
  • Received:2022-08-17 Online:2024-02-28 Published:2024-02-04

Abstract:

Porphyromonas gingivalis(P. gingivalis), a key pathogen of periodontitis, not only harms oral health, but also has an important relationship with the development of many extraoral diseases, such as non-alcoholic fatty liver disease. P. gingivalis and its products can promote the development of non-alcoholic fatty liver disease through hematogenous and intestinal pathways. In this paper, the pathway and possible internal mechanisms involved are briefly described.

Key words: Porphyromonas gingivalis, periodontitis, non-alcoholic fatty liver disease, hematogenous pathway, intestinal pathway

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