Stomatology ›› 2025, Vol. 45 ›› Issue (11): 876-880.doi: 10.13591/j.cnki.kqyx.2025.11.014

• Review • Previous Articles    

Application of cerium oxide nanoparticles in dentistry

TIAN Xue1, YANG Jiahui1, WANG Yuran1, ZHANG Jiahao1, CHEN Yitong1, ZENG Biao1, YANG Yiqiang2()   

  1. School of Stomatology, Ningxia Medical University, Yinchuan 750004, China
  • Received:2024-09-20 Online:2025-11-28 Published:2025-11-18
  • Contact: YANG Yiqiang E-mail:422342115@qq.com

Abstract:

Currently, a wide range of oral antibacterial materials are clinically used, including metal element antibacterial materials(such as silver, zinc, copper, titanium), and non-metal element antibacterial materials(such as fluorine). In recent years, cerium oxide nanoparticles have attracted great interest in the field of oral medicine due to their unique antibacterial, anti-inflammatory, antioxidant, redox capabilities. At the same time, they also have the characteristics of promoting tissue regeneration, inhibiting biofilm formation and good biocompatibility. To enhance the performance of oral materials, nanoparticles have been integrated into products such as composite resins, adhesives, and denture systems. Additionally, they have shown potential for modifying oral ceramic materials and anti-tumor effects.This review focuses on the latest research progress in various fields of oral medicine, including endodontics, periodontology, implantology, prosthodontics, and orthodontics, based on the biological characteristics of nano-cerium oxide. Our goal is to reveal the potential of cerium oxide in the diagnosis and treatment of oral diseases and to provide ideas and references for the expansion of clinical applications in oral medicine.

Key words: cerium oxide nanoparticles, antibacterial, anti-inflammatory, oral medicine

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