牙种植术致严重下颌骨骨髓炎1例及文献回顾

doi:10.13591/j.cnki.kqyx.2025.09.008

Abstract

Abstract:

Dental implant surgery, an established practice, has been widely used in patients with dentition defect. Dental implantation-induced osteomyelitis of the jaw is a rare complication. Osteomyelitis of the jaw is an inflammatory change of the jaw caused by bacterial infection or other physical and chemical factors involving the whole bone tissue, such as periosteum, blood vessels and nerves in the medullary cavity, etc. Due to protracted course and complicated treatment of the disease, the consequences will be serious if not swiftly managed. Here, an unusual case of severe mandibular osteomyelitis following mandibular implant surgery is reported. Also, related literature is reviewed to elucidate the clinical characteristics and management as to highlight the understanding of this complication and provide reference for clinical prevention, diagnosis and treatment.

Key words: mandibular osteomyelitis, dental implant, infection, complication

CLC Number:

CHEN Hongyu, QU Zhuli, CUI Aixuan, WANG Zhaoling. Severe mandibular osteomyelitis following dental implant surgery: A case report and literature review[J]. Stomatology, 2025, 45(9): 687-690.

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References 26

[1]	Roccuzzo A, Imber JC, Salvi GE, et al. Peri-implantitis as the consequence of errors in implant therapy[J]. Periodontol 2000, 2023, 92(1): 350-361.
[2]	唐金鑫, 汤春波, 宋鑫, 等. 牙周炎患者发生种植体周围炎风险预测模型的构建[J]. 口腔医学, 2023, 43(8): 706-710.
[3]	Schlund M, Raoul G, Ferri J, et al. Mandibular osteomyelitis following implant placement[J]. J Oral Maxillofac Surg, 2017, 75(12): 2560.e1-2562560.e7.
[4]	Balanger M, Hinet M, Vacher C, et al. Osteomyelitis of the mandible after dental implants in an immunocompetent patient[J]. Case Rep Dent, 2017, 2017: 9525893.
[5]	Sailer I, Karasan D, Todorovic A, et al. Prosthetic failures in dental implant therapy[J]. Periodontol 2000, 2022, 88(1): 130-144. doi: 10.1111/prd.12416 pmid: 35103329
[6]	Sakka S, Baroudi K, Nassani MZ. Factors associated with early and late failure of dental implants[J]. J Investig Clin Dent, 2012, 3(4): 258-261.
[7]	Ruggiero SL, Dodson TB, Fantasia J, et al. American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw: 2014 update[J]. J Oral Maxillofac Surg, 2014, 72(10): 1938-1956.
[8]	戴悦, 蔡霞, 胡济安. 种植体周病风险评估的研究进展[J]. 口腔医学, 2024, 44(2): 144-147.
[9]	Kniha K, Bock A, Peters F, et al. Microstructural volumetric analysis of the jaw following dental implantation under systemic bisphosphonate delivery: An in vivo and ex vivo rat study[J]. J Periodontol, 2021, 92(7): 66-75.
[10]	Semel G, Wolff A, Shilo D, et al. Mandibular osteomyelitis associated with dental implants. A case series[J]. Eur J Oral Implantol, 2016, 9(4): 435-442. pmid: 27990510
[11]	Cariati P, Perez de Perceval Tara M, Fernandez Solis J, et al. Massive bilateral neck abscess and acute mediastinitis following dental implant surgery[J]. J Craniofac Surg, 2019, 30(6): 1840-1841. doi: 10.1097/SCS.0000000000005602 pmid: 31058725
[12]	Masters EA, Ricciardi BF, Bentley KLM, et al. Skeletal infections: Microbial pathogenesis, immunity and clinical management[J]. Nat Rev Microbiol, 2022, 20(7): 385-400. doi: 10.1038/s41579-022-00686-0 pmid: 35169289
[13]	Sussman HI, Moss SS. Localized osteomyelitis secondary to endodontic-implant pathosis: A case report[J]. J Periodontol, 1993, 64(4): 306-310. doi: 10.1902/jop.1993.64.4.306 pmid: 8483094
[14]	Naval L, Molini MS, Herrera G, et al. Dental implants and osteomyelitis in a patient with osteopetrosis[J]. Quintessence Int, 2014, 45(9): 765-768. doi: 10.3290/j.qi.a32443 pmid: 25126646
[15]	Tarfa RA, Melder K, Mady LJ, et al. Is mandibular osteomyelitis a sequela of SSRI-induced dental implant failure? A systematic review & case report[J]. Am J Otolaryngol, 2022, 43(1): 103236.
[16]	Giovannacci I, Meleti M, Manfredi M, et al. Medication-related osteonecrosis of the jaw around dental implants: Implant surgery-triggered or implant presence-triggered osteonecrosis?[J]. J Craniofac Surg, 2016, 27(3): 697-701. doi: 10.1097/SCS.0000000000002564 pmid: 27092912
[17]	Kellesarian SV, Javed F, Romanos GE. Osteomyelitis arising around osseointegrated dental implants: A systematic review[J]. Implant Dent, 2018, 27(2): 226-235.
[18]	Gargallo-Albiol J, Salomó-Coll O, Lozano-Carrascal N, et al. Intra-osseous heat generation during implant bed preparation with static navigation: Multi-factor in vitro study[J]. Clin Oral Implants Res, 2021, 32(5): 590-597.
[19]	Nagao T, Fukuta J, Sugai T, et al. Prevalence of early and late oral implant loss among smokers: A nationwide survey in Japan[J]. Int J Oral Maxillofac Surg, 2021, 50(8): 1113-1119.
[20]	Dutta SR, Passi D, Singh P, et al. Risks and complications associated with dental implant failure: Critical update[J]. Natl J Maxillofac Surg, 2020, 11(1): 14-19.
[21]	Naseri R, Yaghini J, Feizi A. Levels of smoking and dental implants failure: A systematic review and meta-analysis[J]. J Clin Periodontol, 2020, 47(4): 518-528. doi: 10.1111/jcpe.13257 pmid: 31955453
[22]	Momand P, Becktor JP, Naimi-Akbar A, et al. Effect of antibiotic prophylaxis in dental implant surgery: A multicenter placebo-controlled double-blinded randomized clinical trial[J]. Clin Implant Dent Relat Res, 2022, 24(1): 116-124.
[23]	Ren YL, Weeks J, Xue T, et al. Evidence of bisphosphonate-conjugated sitafloxacin eradication of established methicillin-resistant S. aureus infection with osseointegration in murine models of implant-associated osteomyelitis[J]. Bone Res, 2023, 11(1): 51.
[24]	Camps-Font O, Martín-Fatás P, Clé-Ovejero A, et al. Postopera-tive infections after dental implant placement: Variables associated with increased risk of failure[J]. J Periodontol, 2018, 89(10): 1165-1173. doi: 10.1002/JPER.18-0024 pmid: 29797721
[25]	Yahalom R, Ghantous Y, Peretz A, et al. The possible role of dental implants in the etiology and prognosis of osteomyelitis: A retrospective study[J]. Int J Oral Maxillofac Implants, 2016, 31(5): 1100-1109. doi: 10.11607/jomi.4527 pmid: 27632266
[26]	Velhonoja J, Lääveri M, Soukka T, et al. Deep neck space infections: An upward trend and changing characteristics[J]. Eur Arch Otorhinolaryngol, 2020, 277(3): 863-872. doi: 10.1007/s00405-019-05742-9 pmid: 31797041

Severe mandibular osteomyelitis following dental implant surgery: A case report and literature review

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