口腔医学 ›› 2026, Vol. 46 ›› Issue (4): 309-314.doi: 10.13591/j.cnki.kqyx.2026.04.013

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静电纺丝技术在口腔医学领域应用的研究进展

安群1, 张绍君2, 冯文杰3, 王元非4, 孙德刚3()   

  1. 1 山东医药大学口腔医学院, 山东烟台 (264003)
    2 青岛大学附属青岛市口腔医院修复科, 山东青岛 (266001)
    3 青岛大学附属青岛市口腔医院牙体牙髓科, 山东青岛 (266001)
    4 青岛大学附属青岛市口腔医院中心实验室, 山东青岛 (266001)
  • 收稿日期:2025-07-29 出版日期:2026-04-28 发布日期:2026-04-17
  • 通讯作者: 孙德刚 E-mail:sundegang168@sina.com
  • 基金资助:
    青岛市自然科学基金(23-2-1-165-zyyd-jch);山东省医药卫生口腔内科学重点学科(2025—2027)

Research progress of the application of electrospinning technology in stomatology

AN Qun1, ZHANG Shaojun2, FENG Wenjie3, WANG Yuanfei4, SUN Degang3()   

  1. School of Stomatology, Shandong Medical and Pharmaceutical University, Yantai 264003, China
  • Received:2025-07-29 Online:2026-04-28 Published:2026-04-17

摘要:

口腔疾病的高发病率近年来推动了新型治疗材料的出现。其中,静电纺丝技术能够制备具有良好生物学性能和仿生天然细胞外基质的纳米纤维,因此在口腔医学领域展现出巨大潜力。本文首先简要介绍静电纺丝技术的制备工艺和关键性能,然后根据临床需求,将静电纺纳米纤维在口腔医学各分支学科的研究进展进行分类阐述。最后,针对当前静电纺丝技术在口腔疾病诊治中存在的挑战进行探讨,以期为口腔医学基础研究和临床转化提供有益参考。

关键词: 静电纺丝技术, 纳米纤维, 组织工程, 药物递送, 口腔疾病

Abstract:

In recent years, the high incidence of oral diseases has driven the emergence of new therapeutic materials. Among them, electrospinning technology can prepare nanofibers with good biological properties and mimic the natural extracellular matrix, thus showing great potential in the field of dentistry. This paper first briefly introduces the preparation process and key properties of the electrospinning technology and then classifies the research progress of electrospinning nanofibers in various subdisciplines of stomatology according to the clinical needs. Finally, the challenges of electrospinning technology in the diagnosis and treatment of oral diseases are discussed in order to provide useful references for the basic research and clinical transformation of stomatology.

Key words: electrospinning technology, nanofiber, tissue engineering, drug delivery, oral diseases

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