口腔医学 ›› 2025, Vol. 45 ›› Issue (6): 475-480.doi: 10.13591/j.cnki.kqyx.2025.06.015

• 综述 • 上一篇    

金属-有机骨架在种植体表面改性中的研究进展

倪好1, 李丹雪1,2()   

  1. 1 口腔疾病研究国家重点实验室,国家口腔疾病临床医学研究中心,四川大学华西口腔医学院,四川成都(610041)
    2 四川大学华西口腔医院修复科,四川成都(610041)
  • 收稿日期:2024-04-18 出版日期:2025-06-28 发布日期:2025-07-08
  • 通讯作者: 李丹雪 E-mail: 314525624@qq.com

Research progress of metal-organic frameworks in implant surface modification

NI Hao1, LI Danxue1,2()   

  1. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2024-04-18 Online:2025-06-28 Published:2025-07-08

摘要:

随着种植技术的发展,种植义齿已成为修复牙列缺失和缺损的重要方法。作为种植义齿的关键部分,种植体的表面特性对种植成功率有着极大影响。为提高其生物学性能,对种植体进行表面改性成为口腔种植领域的研究热点。由于其高孔隙率和载药量、可调节的结构和孔道尺寸以及良好的生物相容性等特性,金属-有机骨架材料已成为极具潜力的种植体表面涂层材料,受到越来越多的关注。本文对近年来金属-有机骨架材料在种植体表面涂层中的研究进行了综述,为其在口腔种植领域的进一步应用提供参考。

关键词: 金属-有机骨架, 种植体, 表面改性, 成骨活性, 抗菌活性

Abstract:

As oral implant technology advances, implant prostheses have become an important option for restoring missing teeth. The surface properties of implants, which are a crucial component of implant prostheses, have a significant influence on implant success rate. As a result, surface modification of implants to improve their biological characteristics has emerged as a research hotspot in the field of oral implants. Due to their excellent biocompatibility, high porosity and drug loading, adjustable structure and pore size, metal-organic framework materials have drawn increased attention as promising implant surface coating materials. This paper reviews the research on metal-organic framework materials in implant surface coatings in recent years, and provides a reference for their further application in implantology.

Key words: metal-organic frameworks, dental implants, surface modification, osteogenesis, antibacterial

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