口腔医学 ›› 2026, Vol. 46 ›› Issue (2): 152-155.doi: 10.13591/j.cnki.kqyx.2026.02.012

• 综述 • 上一篇    下一篇

肥胖影响牙周炎的机制研究进展

沈炜炜1, 钟良军1,2()   

  1. 1 杭州师范大学医学部口腔医学院, 浙江杭州 (310000)
    2 杭州师范大学附属医院口腔科, 浙江杭州 (310000)
  • 收稿日期:2025-03-27 出版日期:2026-02-28 发布日期:2026-03-09
  • 通讯作者: 钟良军 Tel:(0571)88303551,E-mail:zymdxx@163.com
  • 基金资助:
    杭州市卫生科技计划重大项目(Z20200046);杭州师范大学研究生创新推进项目(2025HSDYJSKY272)

Progress of research on the mechanism of obesity’s impact on periodontitis

SHEN Weiwei1, ZHONG Liangjun1,2()   

  1. College of Stomatology, School of Medicine,Hangzhou Normal University, Hangzhou 310000, China
  • Received:2025-03-27 Online:2026-02-28 Published:2026-03-09

摘要:

肥胖可能增加牙周炎患病率,加重牙周组织破坏,影响牙周治疗预后。本文旨在总结肥胖相关脂肪因子、氧化应激、口腔菌群、胰岛素抵抗及精神压力变化对牙周炎的影响及潜在机制,以期为临床中综合管理肥胖牙周炎患者提供指导。

关键词: 肥胖, 牙周炎, 慢性炎症, 脂肪因子

Abstract:

Obesity may increase the prevalence of periodontitis, exacerbate the destruction of periodontal tissues, and affect the prognosis of periodontal treatment. This article aims to summarize the effects and potential mechanisms of obesity-related adipokines, oxidative stress, oral microbiota, insulin resistance, and psychological stress on periodontitis, in order to provide guidance for the comprehensive management of patients with obesity and periodontitis in clinical practice.

Key words: obesity, periodontitis, chronic inflammation, adipokines

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