壳聚糖温敏水凝胶在口腔相关组织工程的应用进展

doi:10.13591/j.cnki.kqyx.2024.02.011

Abstract

Abstract:

Chitosan is a natural polymeric polysaccharide derived through deacetylation of chitin. After deacetylation, chitosan can easily interact with DNA, proteins, lipids or negatively charged synthetic polymers, thus possessing unique biocompatibility, degradability and other properties. Chitosan thermosensitive hydrogels are polymeric hydrogels made of chitosan compounded with surfactants, and the hydrogels themselves undergo state changes when the external temperature changes. Because of the good biocompatibility, low tissue immune response and excellent cell adhesion, thermosensitive hydrogels have important applications in tissue engineering, drug carriers and regenerative medicine. In this paper, the applications of chitosan and chitosan thermosensitive hydrogels in oral tissue engineering will be briefly reviewed.

Key words: chitosan, thermosensitive hydrogels, tissue engineering, oral regenerative medicine

CLC Number:

R783.1

Kudelaiti·ABUDUKELIMU , DONG Hongbin, Duolikun·WUFUER . Application advances of chitosan thermosensitive hydrogels in oral-related tissue engineering[J]. Stomatology, 2024, 44(2): 139-143.

References 32

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Application advances of chitosan thermosensitive hydrogels in oral-related tissue engineering

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