纳米氧化铈在口腔领域的应用

doi:10.13591/j.cnki.kqyx.2025.11.014

摘要/Abstract

摘要：

目前,临床广泛使用的口腔抗菌材料涵盖了多种类型,包括金属元素抗菌材料(如银、锌、铜、钛),以及非金属元素抗菌材料(如氟)。近年来,金属氧化铈纳米颗粒在口腔医学领域引起了极大的兴趣,因其具有独特的抗菌、抗炎、抗氧化和氧化还原能力,同时还具有促进组织再生、抑制生物膜形成和良好的生物相容性等特性。为了提升口腔材料的性能,纳米颗粒被整合进复合树脂、粘接剂和义齿系统等产品中。此外,它们还显示出对口腔陶瓷材料进行改性和抗肿瘤的潜力。该综述基于纳米氧化铈的生物学特性,重点探讨其在牙体牙髓、牙周、种植、修复和正畸等口腔医学领域的最新研究进展,揭示氧化铈在口腔疾病诊断和治疗中的潜力,并为口腔临床应用的拓展提供思路和参考。

关键词: 纳米氧化铈, 抗菌, 抗炎, 口腔医学

Abstract:

Currently, a wide range of oral antibacterial materials are clinically used, including metal element antibacterial materials(such as silver, zinc, copper, titanium), and non-metal element antibacterial materials(such as fluorine). In recent years, cerium oxide nanoparticles have attracted great interest in the field of oral medicine due to their unique antibacterial, anti-inflammatory, antioxidant, redox capabilities. At the same time, they also have the characteristics of promoting tissue regeneration, inhibiting biofilm formation and good biocompatibility. To enhance the performance of oral materials, nanoparticles have been integrated into products such as composite resins, adhesives, and denture systems. Additionally, they have shown potential for modifying oral ceramic materials and anti-tumor effects.This review focuses on the latest research progress in various fields of oral medicine, including endodontics, periodontology, implantology, prosthodontics, and orthodontics, based on the biological characteristics of nano-cerium oxide. Our goal is to reveal the potential of cerium oxide in the diagnosis and treatment of oral diseases and to provide ideas and references for the expansion of clinical applications in oral medicine.

Key words: cerium oxide nanoparticles, antibacterial, anti-inflammatory, oral medicine

中图分类号:

R783.1

田雪, 杨佳卉, 王钰然, 章佳豪, 陈怡彤, 曾彪, 杨艺强. 纳米氧化铈在口腔领域的应用[J]. 口腔医学, 2025, 45(11): 876-880.

TIAN Xue, YANG Jiahui, WANG Yuran, ZHANG Jiahao, CHEN Yitong, ZENG Biao, YANG Yiqiang. Application of cerium oxide nanoparticles in dentistry[J]. Stomatology, 2025, 45(11): 876-880.

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