Stomatology ›› 2025, Vol. 45 ›› Issue (12): 946-950.doi: 10.13591/j.cnki.kqyx.2025.12.012

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Application and research progress of lanthanide elements in the field of periodontal diseases

XIE Xiaoyu1,2, LI Yi1()   

  1. Department of Pediatric Dentistry, School of Stomatology, Jilin University, Changchun 130021, China
  • Received:2024-10-28 Online:2025-12-28 Published:2025-12-16
  • Contact: LI Yi E-mail:lyi99@jlu.edu.cn

Abstract:

Rare earth elements, also known as rare earth metals, are a collective term for a series of metal elements in the Earth’s crust, covering 15 lanthanide elements as well as scandium and yttrium. Due to their high electrovalence, active chemical properties, and unique optical, electrical, and magnetic properties, rare earth elements have been widely used in multiple fields such as medical treatment, chemical engineering, and superconductivity. Periodontitis is an inflammatory and destructive disease that disrupts bone balance by triggering an inflammatory response,eventually leading to tooth loss. This article first introduces the antibacterial effect, bone repair effect, antioxidant stress effect, and anti-inflammatory effect of lanthanide elements, and then discusses whether rare earth elements can be used for the treatment of oral periodontitis and peri-implantitis, with the ultimate goal of providing theoretical support for the clinical application of lanthanide elements.

Key words: lanthanide elements, periodontitis, antibacterial, anti-inflammation, bone repair, reactive oxygen species

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