巨噬细胞与牙周炎关系的研究进展

doi:10.13591/j.cnki.kqyx.2025.09.010

摘要/Abstract

摘要：

牙周炎是一种常见的慢性感染性疾病,它的发生是口腔微生物和宿主免疫系统相互作用的结果,免疫系统在调节炎症过程中发挥双重功能。巨噬细胞是固有免疫的组成部分,在牙周炎的发生和消退中发挥重要作用。该文对巨噬细胞在牙周炎中的作用及靶向巨噬细胞治疗牙周炎的相关进展进行综述。

关键词: 牙周炎, 巨噬细胞, 免疫调节

Abstract:

Periodontitis is a common chronic infectious disease resulting from the interaction between oral microorganisms and the host’s immune system. The immune system plays a dual role in regulating inflammation. Macrophages, as a component of innate immunity, play a crucial role in both the onset and resolution of periodontitis. This article reviews the role of macrophages in periodontitis and the recent advances in targeting macrophages for the treatment of periodontitis.

Key words: periodontitis, macrophages, immune regulation

中图分类号:

R781.42

郝艳迪, 刘晔, 高鹏玉, 杨景舒, 徐全臣. 巨噬细胞与牙周炎关系的研究进展[J]. 口腔医学, 2025, 45(9): 696-700.

HAO Yandi, LIU Ye, GAO Pengyu, YANG Jingshu, XU Quanchen. Research progress of the relationship between macrophages and periodontitis[J]. Stomatology, 2025, 45(9): 696-700.

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