光生物调节疗法治疗放射性口腔黏膜炎作用机制研究进展

doi:10.13591/j.cnki.kqyx.2023.12.015

Abstract

Abstract:

Photobiomodulation therapy(PBMT) is a therapeutic method that uses photon energy to affect biological metabolism. As a non-invasive non-drug therapy, it can relieve pain, control inflammation and promote tissue repair. In recent years, the research on the application of PBMT in oral diseases is increasing. Radiation-induced oral mucositis(RTOM) is one of the common complications after radiotherapy for head and neck cancer, with an incidence of 80%-100%. The main clinical manifestations of RTOM are burning pain and ulceration in the mouth, which can lead to severe pain in the submucosa and affect patients’ drinking and eating. Radiotherapy was interrupted in 11% of patients because they could not tolerate RTOM. Related clinical trials have reported that PBMT has a certain effect on relieving RTOM pain and promoting tissue healing. This article reviews the mechanism of PBMT in the treatment of RTOM.

Key words: photobiomodulation therapy, radiation-induced oral mucositis, mechanism

CLC Number:

R781.59

CHEN Jingru,LI Fengdan,JIANG Yinhua. Progress of research on the mechanism of photobiomodulation therapy for radiation-induced oral mucositis[J]. Stomatology, 2023, 43(12): 1134-1139.

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Progress of research on the mechanism of photobiomodulation therapy for radiation-induced oral mucositis

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