微环境下lncRNA介导miRNA调控牙周膜干细胞成骨分化的研究进展

doi:10.13591/j.cnki.kqyx.2024.03.013

Abstract

Abstract:

The study on periodontal tissue regeneration can provide a possible clinical coping strategy for alveolar bone defect. As an important seed cell, periodontal stem cells play an important role in alveolar bone repair. Long non-coding RNA, as competing endogenous RNA, can play an important regulatory role in post-transcriptional levels. This paper reviews the mechanism of lncRNA-mediated miRNA on osteogenic differentiation of PDLSCs under physiological state, inflammatory microenvironment and mechanical stimulation.

Key words: Long non-coding RNA, competing endogenous RNA, microRNA, periodontal ligament stem cells, osteogenic differentiation

CLC Number:

R781.4

PAN Le, DUAN Qinyan, CHENG Junxiang, HONG Feng, HU Yajun. Research progress of LncRNA-mediated miRNA regulating osteogenic differentiation of PDLSCs in microenvironment[J]. Stomatology, 2024, 44(3): 232-236.

References 53

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Research progress of LncRNA-mediated miRNA regulating osteogenic differentiation of PDLSCs in microenvironment

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